Description of the Predominant Clinical Picture in Dengue-covid-19 Coinfection: Review of Reported Cases
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Objective: to describe the clinical features in dengue-covid-19 coinfection in published cases or case series. Methods: we searched PubMed, Scielo and Google Scholar for reported cases of dengue-covid-19 coinfection, MeSH terms of “coinfection-coinfection”, “Dengue”, “covid-19” and “sars-CoV-2” were used. Dengue-covid-19 coinfection publications from January 2020 to August 2023 were included. We excluded duplicate, restricted access, retracted articles and those in which the viruses were not laboratory confirmed. Those in which there was a third acute infectious process, non-simultaneous coinfection and when the result of one of the viruses was a false positive were eliminated. Results: 57 cases were included, the predominant symptoms were fever with 96.5%, general malaise in 54.4% and myalgias in 49.1%. Alarm data such as edema, hepatomegaly, pleural effusion and encephalitis were more frequent in the 0 to 19 years age group. Seven deaths were reported in patients older than 19 years of age. Symptoms associated with death were dyspnea and lethargy. Conclusion: the predominant symptoms identified in the cases studied were fever, malaise and myalgias, which are present in both diseases. In dengue endemic areas, the treating physician should be aware of dengue-covid-19 coinfection in order to provide adequate management and avoid complications due to this cause.
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