Leukocyte death incited by propolis toxicity

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V. C. Tinoco Cabriales
J. A. Quesada Castillo
M. A. Maldonado Ramírez
R. Oliver Parra
B. A. Luna Gojon

Resumen

Objective: The aim of the present study was to assess the extent of propolis’ in vitro cytotoxicity on polymorphonuclear leukocytes. Materials and methods: The present study was an in vitro, controlled, experimental endeavor. Statistical procedure entailed variance analysis of repeated measures as well as Scheffe’s posthoc. A p < 0.05 statistical signifi cance was established. To obtain leukocytes, 10 mL of peripheral venous blood was harvested from six randomly selected, healthy, 20-30 year old subjects, of both genders. Results: Scheffe’s analysis with 95% reliability for comparison between control and experimental groups. Signifi cant with p 0.0001 for propolis 1 control 1 and propolis 2 control 2. For propolis 1 propolis 2 p 0.5002/control 1 control 2 p 0.9621. Conclusions: In the present experiment propolis at a 1:4 dilution applied for 1-2 hours to polymorphonuclear leukocytes caused 70% cellular death. This resulted in statistical signifi cance.

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V. C. Tinoco Cabriales

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Editora de la Revista Ódontológica Mexicana. Órgano Oficial de la Facultad de Odontología, UNAM.

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1.
Tinoco Cabriales VC, Quesada Castillo JA, Maldonado Ramírez MA, Oliver Parra R, Luna Gojon BA. Leukocyte death incited by propolis toxicity. Rev Odont Mex [Internet]. 2019 May 17 [cited 2026 Jun. 8];17(3). Available from: https://revistas.unam.mx/index.php/rom/article/view/69747

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