Vaccine options against PRRS and PCV2 pathogenic viruses of swine, a frequent binomial

Abstract

In the last decade, the porcine reproductive and respiratory syndrome (PRRS) and diseases associated with type-2 Porcine circovirus (PCV2) have become an increasing concern for the swine industry, because they affect production rates and cause substantial economic losses. Currently, most production facilities use classic- type vaccines, elaborated from an attenuated whole virus. As for PCV2, a few new- generation vaccines are available through recombinant DNA technology, whereas only classic vaccines are available against prrsv virus. This articleaims at reviewing the nature of the PRRS and PCV2 viruses as well as highlighting their economic importance, according to national and international incidence data. Additionally, some data about new vaccine options in relation to commercial vaccines has been included. In some cases, low protection against heterologous strains and of strains of recent appearance has also been documented. Research on new-generation vaccines has been well accepted; on the one hand, by the possibility of selecting virus genetic information, which stimulates the protective immune response of the host and, secondly, because it accelerates the development of vaccines, making it possibleto avoid the infections for which the vaccine virus is responsible.