‘‘Green’’ Suzuki-Miyaura cross-coupling: An exciting mini-project for chemistry undergraduate students

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Publicado: feb 28, 2018
DOI: https://doi.org/10.1016/j.eq.2015.11.006

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Bruna Pereira Vargas
Escola de Química e Alimentos, Universidade Federal do Rio Grande --- FURG, Campus Santo Antônio da Patrulha
Clarissa Helena Rosa
Escola de Química e Alimentos, Universidade Federal do Rio Grande --- FURG, Campus Santo Antônio da Patrulha
Diego da Silva Rosa
Escola de Química e Alimentos, Universidade Federal do Rio Grande --- FURG, Campus Santo Antônio da Patrulha
Gilber Ricardo Rosa
Escola de Química e Alimentos, Universidade Federal do Rio Grande --- FURG, Campus Santo Antônio da Patrulha

Resumen

A three-week mini-project is described for an experimental Physical Chemistry or Organic Chemistry course. The activities include synthesis of a biphenyl (4-methoxybiphenyl) via the Suzuki-Miyaura cross-coupling reaction using an adapted domestic microwave oven. The technical skills and concepts that are typically presented in practical chemistry courses are covered, including microwave heating, separation of mixtures, TLC techniques, melting range determination, stoichiometric calculations, and GC---MS techniques

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Educación Química por Universidad Nacional Autónoma de México se distribuye bajo una Licencia Creative Commons Atribución-NoComercial-SinDerivar 4.0 Internacional.
Basada en una obra en http://www.revistas.unam.mx/index.php/req.