Baldwin Rules Update

Abstract

Baldwin’s rules are a before and after in science, especially in organic chemistry. In this work, a bibliographic review of research and advances that was carried out. This topic which may be interest to students that studying advanced organic chemistry and students who are doing research in cyclic systems, as well as professors who are interested in this area. Firstly, about what Baldwin’s rules are and what they used for, how they have evolved, what patterns have been discovered that do not work, or which ones continue to work, as well as new concepts and methodologies or a complement of these to have a successful ring closure in the best conditions. It also talks about the stereoelectronic and geometric characteristics of Baldwin structures, what is most favorable, about applications and use of Baldwin’s rules for important syntheses, and new rules established according to the behavior of molecules with transition metals.